Messina, G., Sirabella, D., Monteverde, S., Galvez, B. G., Tonlorenzi, R., Schnapp, E., De Angelis, L., Brunelli, S., Relaix, F.,Buckingham, M., and Cossu, G. 2008. Skeletal Muscle Differentiation Of Embryonic Mesoangioblasts Requires Pax3 Activity. Stem Cells. In press Morgan, S.C., Lee, H.Y., Relaix, F., Sandell, L.L., Levorse, J.M., and Loeken, M.R. 2008. Cardiac outflow tract septation failure in Pax3-deficient embryos is due to p53-dependent regulation of migrating cardiac neural crest. Mech Dev. 125, 757-767. Lagha, M., Kormish, J.D., Rocancourt, D., Manceau, M., Epstein, J.A., Zaret, K.S., Relaix, F. and Buckingham, M.E. 2008. Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program, Genes Dev. 22, 1828-1837. Morgan, S.C., Relaix, F., Sandell, L.L. and Loeken M.R. 2008. Oxidative stress during diabetic pregnancy disrupts cardiac neural crest migration and causes outflow tract defects. Birth Defects Res A Clin Mol Teratol. 82, 453-463. Daubas, P., Crist, C.G., Bajard, L., Relaix, F., Pecnard, E., Rocancourt, D. and Buckingham, M. 2008. The regulatory mechanisms that underlie inappropriate transcription of the myogenic determination gene Myf5 in the central nervous system. Dev Biol. In press. The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions. Buckingham M, Relaix F. Annu Rev Cell Dev Biol. 2007;23:645-73. Review.
Beta catenin-independent activation of MyoD in presomitic mesoderm requires PKC and depends on Pax3 transcriptional activity. Brunelli S, Relaix F, Baesso S, Buckingham M, Cossu G. Dev Biol. 2007 Apr 15;304(2):604-14. Epub 2007 Jan 9.
Myogenic progenitor cells in the mouse embryo are marked by the expression of Pax3/7 genes that regulate their survival and myogenic potential. Buckingham M, Bajard L, Daubas P, Esner M, Lagha M, Relaix F, Rocancourt D. Anat Embryol (Berl). 2006 Dec;211 Suppl 1:51-6. Epub 2006 Oct 13. Review.
A novel genetic hierarchy functions during hypaxial myogenesis: Pax3 directly activates Myf5 in muscle progenitor cells in the limb. Bajard L, Relaix F, Lagha M, Rocancourt D, Daubas P, Buckingham ME.Genes Dev. 2006 Sep 1;20(17):2450-64.
Skeletal muscle progenitor cells: from embryo to adult. Relaix F. Cell Mol Life Sci. 2006 Jun;63(11):1221-5. Review. Pax7 and myogenic progression in skeletal muscle satellite cells. Zammit PS, Relaix F, Nagata Y, Ruiz AP, Collins CA, Partridge TA, Beauchamp JR. J Cell Sci. 2006 May 1;119(Pt 9):1824-32. Epub 2006 Apr 11.
Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells. Relaix F, Montarras D, Zaffran S, Gayraud-Morel B, Rocancourt D, Tajbakhsh S, Mansouri A, Cumano A, Buckingham M. J Cell Biol. 2006 Jan 2;172(1):91-102. Epub 2005 Dec 27. Erratum in: J Cell Biol. 2007 Jan 1;176(1):125.
Pax3/Pax7-dependent population of skeletal muscle progenitor cells. Lagha M, Rocancourt D, Relaix F. Med Sci (Paris). 2005 Oct;21(10):801-3. French.
Direct isolation of satellite cells for skeletal muscle regeneration. Montarras D, Morgan J, Collins C, Relaix F, Zaffran S, Cumano A, Partridge T, Buckingham M. Science. 2005 Sep 23;309(5743):2064-7. Epub 2005 Sep 1.
A Pax3/Pax7-dependent population of skeletal muscle progenitor cells. Relaix F, Rocancourt D, Mansouri A, Buckingham M. Nature. 2005 Jun 16;435(7044):948-53. Epub 2005 Apr 20.
Divergent functions of murine Pax3 and Pax7 in limb muscle development. Relaix F, Rocancourt D, Mansouri A, Buckingham M. Genes Dev. 2004 May 1;18(9):1088-105.
The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo. Relaix F, Polimeni M, Rocancourt D, Ponzetto C, Schäfer BW, Buckingham M. Genes Dev. 2003 Dec 1;17(23):2950-65.
The formation of skeletal muscle: from somite to limb. Buckingham M, Bajard L, Chang T, Daubas P, Hadchouel J, Meilhac S, Montarras D, Rocancourt D, Relaix F. J Anat. 2003 Jan;202(1):59-68. Review.
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